Evidence-based · No agenda
Topics I was interested in and researched, published here without an agenda beyond a desire to share what I’ve learned.
The story is more complicated than either side admits. The cardiovascular “debunking” was itself partially debunked in 2025. The atrial fibrillation risk signal was a statistical artifact. A 2026 NEJM trial showed a 43% reduction in cardiac events — in the right population.
Nicotine is one of the most pharmacologically broad-spectrum neuromodulators known to science — with documented effects on depression, attention, cognition, neuroprotection, and arousal. A rigorous look at the evidence for and against, the clinical findings across psychiatry and neurology, and why this molecule has been systematically ignored.
A resource for understanding how insurance estimates work, why initial payouts are systematically low, and what you can actually do about it. The system is designed to be confusing. This makes it less so.
No matching explorations.